We investigate the interplay between shape anisotropy and a stress-based uniaxial anisotropy on the magnetic domain structure of La0.7Sr0.3MnO3 nanoelements as a function of aspect ratio, using micromagnetic simulations. We show that a direct competition between the anisotropies gives rise to high energy multi-domain flux closure configurations, whilst an alignment of the anisotropies can modify the effective element dimensions and act to stabilise a single domain configuration. Our results demonstrate the ability to control the spin state of La0.7Sr0.3MnO3 elements in addition to tailoring the domain wall width by controlling the anisotropy of the material, which is key for spintronic applications that require a high spin-polarization and stable magnetic configurations.